Dexter’s school and parents decide to send him to college. He ignores his fellow students, who prefer to “party now, study later”, until his mind finally snaps from the workload.
In a parody of Tom and Jerry, Dexter accidentally switches his brain with that of a mouse’s and must avoid his mother when she decides to exterminate him.
It is Career Day, and because Dexter is ashamed of his father, he creates a better father for himself. However, he soon discovers that his real father is much cooler.
Not interested in hearing Dee Dee’s long-winded story, Dexter gives her a silencing formula to keep her quiet, but it instead turns her into a giant monster still bent on telling her story. When he realizes that nothing can make her quiet, he becomes a giant monster himself.
After being denied dessert by his parents for not eating his vegetables, Dexter uses radiation therapy so that he can like vegetables, but it causes a severe side effect that turns him into an Incredible Hulk-like character if he goes too long without them.
When an electrician comes to Dexter’s house to repair a blown-out fuse, he accidentally stumbles onto his laboratory, and Dexter enlists him to repair the lab.
After a crime prevention talk at school, Dee Dee, Lee Lee, and Mee Mee become crime fighters, but they unintentionally end up being neighborhood criminals.
Mandark brings his lab duck Ducky for show and tell to counter Dexter and his lab monkey. Though neither creature displays remarkable characteristics at school, Ducky, unbeknownst to Mandark, is the alter ego of supervillain Quackor the Fowl.
Dexter decides to work with Mandark, but finds himself doing all of the work. In the end, Mandark tries to press the button when Dexter connects the plug in the outlet to bring his show title back.
When his television show is interrupted by the Emergency Broadcast System, Dexter sets about fixing any emergencies in the neighborhood to make the signal go away.
Dad decides to give the car a retouch, but keeps breaking things and saying he will fix it later. After having enough, he pushes the car over a cliff, and below it are other crushed cars, meaning this was not the first time.
Dexter and Dee Dee’s father buys a video game for them to play, but the game sucks Dexter inside when he plugs in the cartridge, and it is up to Dee Dee to bring him out.
Dexter catches the chicken pox, and Dee Dee tells him a ridiculous tale that if he keeps scratching them, he will turn into an evil chicken. Dexter completely restrains himself so that he will not have to scratch it; unfortunately, he is unable to resist and his nonstop scratching eventually does just that.