Tom gets Spike sent to obedience school for being naughty, and Jerry is left without a protector. When Spike returns, Tom tries hard to get Spike to revert to his old ways. Jerry fights back to make sure that Spike keeps his cool.
Ginger and Rick decide to bring Tom and Spike along on their Hawaiian vacation, but on their plane flight, Jerry and Tuffy tag along as well. Tom and Spike get loose out of their cages, and before long, things go awry.
An unlucky dog named Dutch goes to Detectives Tom and Jerry, saying that a ruby stone he has been guarding from his great grandfather’s master pirate “Captain Wrongway Weston” is taken from a female dog named Roxy, who is also unlucky.
Tom is under strict orders to not wake the witch sisters, but Jerry is set on getting Tom in trouble. When Tom uses the magic spell wand and makes all of the furniture come alive, he must get the help of Newt to make everything go back as it was.
Rick and Ginger’s vacation continues on a cruise ship, where to make sure Tom and Spike don’t cause havoc, they keep them in the carriers. Jerry and Tuffy invade their vacation again, and Meathead, the ship’s cat, hunts down Jerry and Tuffy on the ship.
After the plane incident, Rick and Ginger sneak Tom and Spike at “Paradise Resort” where pets are not allowed, but when Rick and Ginger leave Tom and Spike in their room, Jerry and Tuffy cause them trouble.
Tom has a date with Toodles and she warns him not to be late, but Butch tricks Tom that Toodles has a surprise in the basement for him and he leaves him down there; Toodles leaves Butch in charge of her younger, rowdy siblings; Jerry and Tuffy watches a horror movie and mistakes Tom for […]
Detectives Tom and Jerry are hired by Polly the Dog to get back her collar from mean Barkley at the park. After a series of incidents involving the pound “jail” and an electric fence, Barkley reforms when he meets Polly and falls in love with her.
Dr. Bigby upgrades his robot to be “The future of home security,” but when Tom invades the lab to pursue Jerry and Napoleon, the robot has some tricks up its sleeves which will lead the robot into hysteria.
When Hildie and Beatie go away on a vacation, Tom and Jerry has problems when their ghost nephew, Grayson, comes over and throws a large party with his friends and takes their crystal ball for bowling.
Jerry and his friend Napoleon are lab mice and Tom is outside going through trash until he sees the two mice that he wants for an appetite and things go crazy when Dr. Bigby’s elderly cat becomes a vicious kitten and chases the mice.
Little Quacker enlists Jerry’s help in getting his cracked favorite birdbath fixed, but they get distracted by the smell of Tom’s delicious Chinese takeout. After fighting over the food, Tom steals Little Quacker’s fortune cookie and gets the kind of fortune he deserves.