Dexter is forced to take Dee Dee to the zoo. There, she ends up trying to save an ostrich with disastrous results. Dee Dee and the ostrich switches their places.

Major Glory, Krunk, and Valhallen try to rid their apartment of a bee.

Dexter turns Dee Dee into a boy, but is disappointed when “he” is not a genius as Dexter would like it.

Dexter and Dee Dee experiment with coffee after seeing how it energizes their parents in the morning.

Dexter reluctantly takes piano lessons from Professor Williams (Paul Williams), but when the Professor stumbles onto Dexter’s lab, he discovers that Dexter has more musical talent than he thought.

When Dexter’s nightmares become frequent and problematic, he invents a machine that allows him to have nice dreams, as long as Dee Dee can operate it properly while she is awake.

Mandark enters a surfing contest and tries to cheat his way to victory to win Dee Dee’s heart from another surfer.

Dexter’s father tries to get himself and Dexter to his fishing spot before sunrise so that they can start fishing before others arrive.

When Krunk gets a tortilla chip stuck in his tooth, Major Glory decides to fix it by pulling the tooth out himself against Valhallen’s admonition to take him to the dentist as they have the tools to take the chip out properly.

Dexter’s parents remember their first date and dance together.

Dexter creates a robot to assist him, but the robot starts controlling his lab and tries to destroy Dexter.

Dee Dee enters the land of her imaginary friend Koosalagoopagoop.

Rerun of “Dexter’s Laboratory”, the first What a Cartoon! pilot.

Dexter’s lab is threatened with repossession unless he can repay his debt to NASA. When Dee Dee wins the same amount in a lottery, he decides to steal her money out of desperation.

When his television show is interrupted by the Emergency Broadcast System, Dexter sets about fixing any emergencies in the neighborhood to make the signal go away.

When Dexter gets amnesia, Dee Dee decides to play tricks on him by creating a whole new identity for him in her image.

When Dee Dee tries to cut off a piece of her hair, she accidentally cuts off one of her pigtails. Dexter gives her a potion to make her missing hair grow back. However, Dee Dee squirts too much of it in her hair, and Dexter must return Dee Dee’s hair back to normal.

To fix their apartment’s plumbing, Krunk and Valhallen go to the basement, where they meet Ratman (Maurice LaMarche), a diminutive vigilante raised by rats (a parody of Batman).

Dexter thinks that a crazy homeless person balancing electronic devices on his head and muttering gibberish is a genius trying to contact aliens, so he takes him home.

Dexter and Dee Dee enter tryouts to become Major Glory’s sidekick. When Dee Dee wins, Dexter realizes that fancy costumes are not the only criterion to become a superhero.

After a crime prevention talk at school, Dee Dee, Lee Lee, and Mee Mee become crime fighters, but they unintentionally end up being neighborhood criminals.

Dexter’s father plays golf with his kids.

When Dee Dee takes photographs of his lab, Dexter goes on an adventure to retrieve the photos before his parents see them.

Dexter falls in love with a new girl at his school, but he cannot win her heart until Dee Dee helps him with poetry