Monkey encounters Simion (Maurice LaMarche), an intelligent anthropomorphic chimpanzee who seeks vengeance on humans for turning him into his current state.
After Dee Dee declares that she can beat Dexter in any game, Dexter challenges her to a series of games in his lab, though he prefers to win by cheating.
After Dexter orders and eats a giant burrito, he suffers severe stomach pains. Believing a test the computer gave him, he assumes that he has only 30 minutes to live.
Dexter creates a satellite to clean stains off of his clothes, but it goes horribly wrong when Mir space station hits the satellite that Dexter created and the satellite becomes damaged, causing the fabric beneath each stain to be eliminated as well.
After Dexter’s pencil rolls to the back of the school bus, Dexter goes to retrieve it, but legend says that no one has ever returned from the back of the bus.
After fellow Justice Friend White Tiger helps Valhallen stop a super-villain, the latter invites him to spend the night in his apartment, forgetting that Major Glory is allergic to cats.
Dexter decides to work with Mandark, but finds himself doing all of the work. In the end, Mandark tries to press the button when Dexter connects the plug in the outlet to bring his show title back.
Mandark disguises himself as Dexter’s mom to get into Dexter’s Lab. Unfortunately for Mandark, he now has to deal with Dexter, Dad, and Dee Dee’s requests, which are too much for him.
In need of an assistant to operate his latest invention, Dexter performs a brain transplant on Dee Dee to make her smart enough to fulfill the role. With her new brain, Dee Dee proves to be more intelligent than Dexter.
When Dee Dee frees one of Dexter’s robots by removing the wrench that froze it, the robot tries to destroy anyone who is mean to Dee Dee, including her friends, her mother and Dexter himself.
Dexter accidentally gives himself telepathy that he cannot shut off when trying to overhear his father’s thoughts to figure out what he got for his birthday, causing everyone to accidentally read his own mind.