Dexter falls victim to one of his own inventions and sends Dee Dee back in time to warn his past self about the consequences, but the past Dexter proves hard to convince.
In a parody of Tom and Jerry, Dexter accidentally switches his brain with that of a mouse’s and must avoid his mother when she decides to exterminate him.
Dexter and Dee Dee enter tryouts to become Major Glory’s sidekick. When Dee Dee wins, Dexter realizes that fancy costumes are not the only criterion to become a superhero.
Dexter’s lab is threatened with repossession unless he can repay his debt to NASA. When Dee Dee wins the same amount in a lottery, he decides to steal her money out of desperation.
Mandark Astronomanov, a new student at Dexter’s school, seems to be superior to Dexter academically. Mandark forces Dexter to shut down his lab so that Mandark’s lab can gain more power. However, with the help of Dee Dee, Dexter manages to destroy Mandark’s lab.
When Dexter is bitten by a clown’s dentures, he begins turning into a mad clown every night, terrorizing the town with his mayhem, and only Dee Dee, who knows mime, can stop him.
Banned from watching a late-night movie due to his young age, Dexter uses his technology to artificially grow into adulthood, but Dee Dee tampers with his machine, causing Dexter to turn into an old man.
To prevent himself from being taken away by aliens for experimentation, Dexter tricks Dee Dee into going instead, but he regrets his decision after realizing how much he cares for her.