Dexter and Dee Dee’s father buys a video game for them to play, but the game sucks Dexter inside when he plugs in the cartridge, and it is up to Dee Dee to bring him out.

Dee Dee wins a golden diskette, earning her a free trip to the laboratory of Professor Hawk (Tom Kenny), one of Dexter’s favorite scientists.

Mandark brings his lab duck Ducky for show and tell to counter Dexter and his lab monkey. Though neither creature displays remarkable characteristics at school, Ducky, unbeknownst to Mandark, is the alter ego of supervillain Quackor the Fowl.

Dexter accidentally gives himself telepathy that he cannot shut off when trying to overhear his father’s thoughts to figure out what he got for his birthday, causing everyone to accidentally read his own mind.

After Dee Dee declares that she can beat Dexter in any game, Dexter challenges her to a series of games in his lab, though he prefers to win by cheating.

Dexter’s parents remember their first date and dance together.

Dee Dee accidentally shuts down Dexter’s lab, and he has to power it back. In the process, Dee Dee attempts to keep Dexter from finding out what she really did.

Dexter’s father tries to watch a golf tournament, but is constantly interrupted by his wife, Dexter, and Dee Dee.

Rerun of the second What a Cartoon! pilot.

Dee Dee’s new dance moves annoy Dexter to no end.

Dexter pirates cable for his father.

Dexter’s school and parents decide to send him to college. He ignores his fellow students, who prefer to “party now, study later”, until his mind finally snaps from the workload.

When Dexter becomes the victim of Dee Dee’s snowballs, their father teaches him to be the snowball terror that he used to be in his youth.

When Dexter’s father tries to teach his son sports, he realizes that Dexter is not athletic.

Dee Dee uses Dexter’s growth formula on the plants in the garden, which causes them to grow to an enormous size……and man-eating monsters as well.

Since his studying is interrupting his favorite TV shows, Dexter creates a helmet to absorb the shows directly. However, the plan backfires when he randomly snaps into television-based outrages.

While out for dinner at a pizza restaurant, Dexter tries to slow down the “Whack the Weasel” machine to win a stuffed Monkey doll before Dee Dee does. Security captures him for tampering with the machine, and he falls into the hands of a mad scientist.

Dee Dee gets a song stuck in her head, which is actually a virus. Dexter and Mom soon catch it, and Dexter has to reverse the effects of this. He succeeds at the end, not knowing that Dad also caught it.

Dexter and his father enter a golf tournament, but Dexter’s father proves inept at the sport.

Dexter creates a device that turns people into hideous blobs. His parents then sell the device in a garage sale, where it ends up in Mandark’s hands.

Dexter creates a device to make a lifelike superhero comic, with his sister villain “Deestructa”.

Dexter, Monkey, Agent Honeydew, the Justice Friends, Dee Dee, her imaginary friend Koosalagoopagoop, Mandark, his parents, and Dexter’s parents participate in a cross-country race a la Wacky Races.

Two robots (Martin Mull and Fred Willard) escape from Dexter’s lab in order to have a better life and avoid Dexter’s totalitarian rule.

Dexter is upset that Dee Dee is more photogenic than him, so he transforms his face into a handsome one for his next Picture Day.