The Leader has placed an expanding dome of pure gamma radiation around the Cube, with anyone caught inside it being mutated into a Gamma Monster. The Avengers, along with the support of S.H.I.E.L.D., enter the Cube in an attempt to the destroy the Gamma Generator.

Lost and separated, the Avengers struggle to survive in the Nine Realms.

The Skrulls’ invasion of Earth has begun – and Wakanda is the first target. Ms. Marvel comes to the rescue, but must deal with both a stubborn Black Panther and a team of Skrulls posing as the Avengers.

Enraged by Tony Stark buying out his company, Simon Williams becomes a deadly being of ionic energy, Wonder Man, in order to exact revenge. Meanwhile, Wasp and Thor chase a group of A.I.M. agents to find their secret hideout and run into another villain, MODOK.