Cow and Chicken unwittingly create perpetual energy through spilling a junior chemistry set. This leads Rear Admiral Floyd (the Red Guy) to a get-rich scheme.
While trying out the Pork Butt catapult, Chicken is accidentally swallowed by Cow. Mom and Dad take her to a doctor (the Red Guy), and they must get Chicken back out before he journeys through all four of Cow’s stomachs.
Cow and Chicken’s anarchic cousin, Sow, comes over for a visit. When she comes over to school, Cow ends up taking the blame for Sow’s misguided actions.
The family heads over to Oregon to find a tribe of head-hunters. Eventually, Chicken soon becomes the “hunted”, especially when the Red Guy is their leader.
Chicken receives a credit card (which only has 25 cents worth of credit) inside his cereal. He and Cow are both stalked by the Red Guy over the fee they have to pay after purchasing some gum.