As part of a school assignment, Cow and Chicken write essays on what jobs they want when they’re older. Since Cow’s essay won, she gets to live her dream as an astronaut, whereas the runner-up, Chicken, works at a supermarket
Chicken’s wish for Cow to shut up comes true. When he is run over by a truck, he regrets it after being sentenced to 50 years in prison for jaywalking (although the truck driver was at fault) when Cow refuses to clear his name.
It’s the Egyptian times, and Weasel and I.R. are both asp exterminators, attempting to save the queen Cleopantless (The Red Guy) from this infestation.
The family heads over to Oregon to find a tribe of head-hunters. Eventually, Chicken soon becomes the “hunted”, especially when the Red Guy is their leader.
After being sold an invisibility potion by the Red Guy, Cow really believes she is invisible, despite not drinking it. She goes on to cause trouble, in which she, somehow, gets away with.
Cow and Chicken’s anarchic cousin, Sow, comes over for a visit. When she comes over to school, Cow ends up taking the blame for Sow’s misguided actions.
Cow gets a part time job at a milk farm in order for her to get a Crabs the Warthog doll. When Chicken tries to apply for a part time job, he soon ends up in danger.
Whilst in prison, Weasel explains his crime when he stalked I.R. Baboon as a subject for a wildlife study, which turns out to all be a bad weasel dream that Cow had.