Cow and Chicken unwittingly create perpetual energy through spilling a junior chemistry set. This leads Rear Admiral Floyd (the Red Guy) to a get-rich scheme.
Sick and tired of the ketchup-based meals being served at school by Mrs. Barederriere (the Red Guy), Cow and Chicken follow in their grandparents’ footsteps and make a food stall that serves meat.
As part of a school assignment, Cow and Chicken write essays on what jobs they want when they’re older. Since Cow’s essay won, she gets to live her dream as an astronaut, whereas the runner-up, Chicken, works at a supermarket
Serving a 99-year sentence at a correctional facility with I.R. Baboon, Weasel starts to feel concerned about the inhumane correctional devices that are set up on fellow prisoners.
Weasel and I.R. investigate to see who has done the heinous crime of erasing Cow and Chicken out of existence. Eventually they discover that the culprit is the Red Guy trying to take over the show, and this was all a dream Cow had.
After being sold an invisibility potion by the Red Guy, Cow really believes she is invisible, despite not drinking it. She goes on to cause trouble, in which she, somehow, gets away with.
Weasel is an aircraft pilot, with I.R. as his co-pilot. Their job is to bring passengers upstream because of a dam, created by beavers, getting in the way. However, things go wrong when there’s too much weight aboard.
While trying out the Pork Butt catapult, Chicken is accidentally swallowed by Cow. Mom and Dad take her to a doctor (the Red Guy), and they must get Chicken back out before he journeys through all four of Cow’s stomachs.