After watching a Ron Pickles TV special, Melissa begins cracking jokes at her friends, annoying them and eventually upsetting Lola. After a talk with Granny, she makes it up to her friends with comical speech.
Granny takes the babies to the hospital for their flu shots, but Bugs and Daffy manage to elude their turn for a shot! In getting ill, Bugs and Daffy miss all the fun the others have.
The babies overhear what they assume is that Granny is moving to a new house and they reminisce the times they enjoyed inside the house. It is revealed that all Granny wants to move around and not move to a new house.
Marvin the Martian pays a visit to the babies, but no one likes him so Taz befriends Marvin to make him feel welcome. Then everyone else feels the same.
Floyd takes the babies to the museum, whilst Bugs’ dream of flying to the moon is shattered until, Taz gets them all tangled in the space experience zone.
On a day at the beach, Melissa gets frustrated that she can’t have a new spade and makes friends with a baby turtle she calls Myrtle. Melissa wants to keep her, but learns she can’t take her from her natural habitat.
Pepe tours the babies around the Acme gardens finding a place to plant a lemon tree. Eventually everyone gets irritated by Pepe’s stink, upsetting him, but they rejoin him and Pepe introduces them to his pal Gossamer.
Daffy and Melissa stick together to play impractical jokes on the others. To get even, Lola demonstrates the consequences of an impractical joke to Daffy and Melissa.
With Lola’s hair getting in her eyes, Melissa attends to it with hair gel only for Lola to get laughed at. Granny arranges for a hairdressing appointment but Lola has second thoughts about it, until Granny coaxes her.
Floyd takes the babies to a mini-golf course. Finding himself without a chance of winning, Daffy cheats, whilst Tweety scores down the hole every time. Daffy realises the game lies more in the fun than the winning score.
Floyd takes the babies to the green screen for their picture to be taken. Daffy, disappointed at the choice of scene, spoils Bugs’ appearances on the green screen until the photographer gets his priorities right.
Bugs, Daffy, and Lola argue what the material of the moon is. Floyd takes them and Taz to the library for research. They find hard to refrain from making noise, but they manage to find the information they were looking for.
Floyd takes the babies on a long journey to the Acme Garlic Festival. All the while they try to pass the time giving Floyd a tiresome time. Floyd’s car breaks down and they miss the festival but they get some garlic souvenirs.
Floyd take the babies to Auntie’s Bakery, where they love cinnamon rolls, but unfortunately the bakery’s business is due to close down. Everyone works hard to get the bakery in the book of world records so that its left standing.