While listening to his favorite hip hop music, Jerry gets disrupted by the noise of the city, so he moves out of town to a farm owned by Tom. As a result, his music causes Tom’s pet hen to lay eggs quickly.
Upon seeing Tom unable to catch Jerry, Butch recruits the former to join the League of Cats, a secret organization of cats who work together to catch mice.
Tom works at a zoo run by Spike, who orders him never to feed the zoo’s animals (only Spike can) or else he will have his badge. However, Jerry inadvertently and constantly causes trouble by framing Tom while he tries to prevent Jerry from feeding them.
Nancy, Tom’s owner from Baby Puss (1943), brings Tom to her elementary school for show-and-tell in which she wants Tom to win the gold star for best pet.
A sequel to Pecos Pest (1955), Jerry’s uncle, Pecos Pest, returns to Tom and Jerry’s house for a visit, where he constantly sings and plays on his guitar, annoying and keeping both Tom and Jerry awake.
At a laboratory, Jerry, using a virtual reality setup, plays a game in which Tom is hated by Mrs. Two-Shoes (while she likes Jerry) and is scared of Jerry. When Tom arrives at the laboratory, he plays a game in which Spike is scared of him (albeit still talking while Tom still does not).