The Chameleon, an international spy, attempts assassination on two diplomats in order to derail the signing of a peace proposal. S.H.I.E.L.D. director Nick Fury enlists Jameson’s help to prevent the Chameleon’s crime, while Spider-Man begins his own hunt against the assassin.

Spider-Man begins to worry about his growing mutation. In order to seek a cure, he heads to the Xavier mansion, where he encounters the X-Men. A brief fight occurs, after which Spider-Man explains his plight to Charles Xavier, who tells Spider-Man that he cannot cure him. Beast tells Spider-Man to go to Herbert Landon, who […]

Peter Parker / Spider-Man discovers that his science teacher, Dr. Curt Connors, has been turned into a deranged lizard due to an experiment gone wrong, and is abducting people throughout Manhattan.

Spider-Man grieves over Mary Jane’s loss following his battle against the Green Goblin. Meanwhile, Tombstone, whilst incarcerated in Ryker’s Island, plots revenge on Robbie for previously causing his arrest. In exchange for assisting cell-mate Richard Fisk in a few brawls in prison, Richard requests that his father frame Robbie as a criminal mastermind.

Peter and Robbie visit Omar Mosely, who tells them about the story of the Six American Warriors. During World War II, after the creation of Captain America, five more heroes were made: Whizzer, Miss America, the Thunderer, the Destroyer, and the Black Marvel. They fought alongside Captain America. Now in the present, Spider-Man must find […]

The Hobgoblin defeats Wilson Fisk and declares himself the new Kingpin of Crime. Fisk then asks Osborn to assist him in reclaiming his position.

Tombstone is hired by Silvermane’s daughter Alisa to destroy the story planned for the Daily Bugle revealing that she had taken over her father’s criminal organization. Tombstone attempts to use Robbie Robertson, whom he was childhood friends with, to kill the story, using Robbie’s teenage son Randy to do it.

Peter and Mary Jane are ready to tie the knot. Their plans are interrupted, however, when the Scorpion kidnaps May. Spider-Man gives chase and rescues May, but wonders if the fates are trying to tell him something. Meanwhile, Kingpin is paying for Peter and Mary Jane’s wedding. When the wedding finally takes place, a still […]

Madame Web brings Spider-Man to another dimension where he is brought before a being known as the Beyonder, who has chosen Spider-Man to be part of an experiment to see if good is more powerful than evil. He finds a paradise planet and chooses Doctor Octopus, Doctor Doom, Alistair, the Lizard, and the Red Skull […]

Spider-Man’s horrifying genetic mutation reaches its culmination as he transforms into the Man-Spider. Dr. Crawford summons Kraven to help her track down Spider-Man and cure him of his mutation with a newly developed antidote.

The vampire hunter Blade arrives in New York City to destroy Morbius, but Spider-Man wants to revert Morbius back into his human form.

Spider-Man is taken to an alternate dimension where due to a series of events, its native Peter has bonded with the Carnage symbiote to become the maniacal Spider-Carnage, who has devastated and demolished New York City with the aid of Kingpin, Alistair, the Hobgoblin, and the Green Goblin. The Beyonder tells Spider-Man that his deranged […]

In a battle with Doctor Octopus, a medical research building is destroyed. Blaming himself, Peter is considering giving up being Spider-Man, when he meets an inter-dimensional being named Madame Web and his biggest fan, a little girl called Taina, who Spider-Man shares his origin story with. Doctor Octopus attacks with his new invention, the Octobot.

Spider-Man and Daredevil attempt to clear Peter’s name. Daredevil informs Spider-Man of Wilson Fisk’s true identity as the Kingpin. As Spider-Man battles the Chameleon, the stage is set for a fateful showdown between Daredevil and Kingpin.

Mary Jane is revealed to have new found water-based powers like Hydro-Man. Spider-Man follows Hydro-Man to an underwater lab, where he discovers that scientist Miles Warren has used his controversial cloning technology to create a clone of the original Hydro-Man. He is even more shocked to learn that Warren then used a drop from Hydro-Man […]

An increasingly desperate Spider-Man drinks the serum designed to cure him, but it makes him grow four extra arms. The antihero known as the Punisher thinks Spider-Man is a crook and chases him around. Spider-Man finds out that Morbius has turned into a vampire and is draining people’s blood to survive. Spider-Man wants to help […]

Spider-Man tells Felicia that he can’t have a girlfriend. She understands this, but wants Spider-Man to know how she feels about him. Meanwhile, Jackson Weele leads a gang of thieves armed with jet-pack technology. Weele has developed a large gyro-wheel in which he uses to plunge through the city. Peter wants to ask Felicia to […]

Osborn hires the Hobgoblin to assassinate Kingpin, because of the crime lord’s continuous threats against him. Peter saves Kingpin just as the Hobgoblin attempts an attack on him. After eluding Spider-Man, the Hobgoblin is fired by Osborn as of his unsuccessful assassination on Kingpin.

As Peter goes to an interview with scientist Mariah Crawford, she is under attack by the villain Kraven the Hunter. After Spider-Man is able to elude him, Dr. Crawford explains that Kraven and her used to be in love but when he was seriously injured by lions she had no choice but to give him […]